Modification of porous polyethylene scaffolds for cell attachment and proliferation
نویسندگان
چکیده
Synthetic polymers are widely researched for their use in tissue engineering. Control in size, surface area, pore size, and elasticity are the biggest advantages of using a man-made polymer. However, often the polymers are hydrophobic (do not encourage cell attachment); hence, it is hugely challenging to integrate them with the normal tissues. Herein, we have tried to overcome this disadvantage of polymers by coating them with citrate-stabilized gold nanoparticles and arginine. High-density polyethylene, upon multiple treatments, shows low water contact angle, which encourages cell attachment and proliferation in comparison to the untreated polymers.
منابع مشابه
The Role of Biodegradable Engineered Nanofiber Scaffolds Seeded with Hair Follicle Stem Cells for Tissue Engineering
Background: The aim of this study was to fabricate the poly caprolactone (PCL) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (HFSC) in the graft material using electrospun PCL nanofiber scaffold for tissue engineering applications. Methods: The bulge region of rat whisker was isolated and cultured in DMEM: n...
متن کاملEffect of Different Manufacturing Methods on the Conflict between Porosity and Mechanical Properties of Spiral and Porous Polyethylene Terephthalate/Sodium Alginate Bone Scaffolds
In order to solve the incompatibility between high porosity and mechanical properties, this study fabricates bone scaffolds by combining braids and sodium alginate (SA) membranes. Polyethylene terephthalate (PET) plied yarns are braided into hollow, porous three dimensional (3D) PET braids, which are then immersed in SA solution, followed by cross-linking with calcium chloride (CaCl₂) and dryin...
متن کامل3D Scaffold Designing based on Conductive/Degradable Tetrapolymeric Nanofibers of PHEMA-co-PNIPAAm-co-PCL/PANI for Bone Tissue Engineering
The hydrophilic, conducting, biocompatible and porous scaffolds were designed using poly(2-hydroxy ethyl methacrylate)-co-poly(N-isopropylacrylamide)-co-poly(ε-caprolactone) (P(HEMA-b-NIPAAm-b-CL))/polyaniline (PANI) for the osteoblast applications. To this end, the PHEMA and P(HEMA-b-NIPAAm) were synthesized via reversible addition of fragmentation chain transfer (RAFT) polymerization, and in ...
متن کاملComparing Behavior of Chondrocyte Cells on Different Polyhydroxybutyrate Scaffold Structure for Cartilage Tissue Engineering
Introduction: As the ability to repair cartilage tissue in body is limited, finding a suitable method for cartilage regeneration has gained the attention of many scholars. For this purpose, scaffold structure and morphology, along with cell culture on it, can be a novel method to treat cartilage injuries, osteoarthritis. Methods: In this study, polyhydroxybutyrate (PHB) is selected as the scaf...
متن کاملHybrid Macro-Porous Titanium Ornamented by Degradable 3D Gel/nHA Micro-Scaffolds for Bone Tissue Regeneration
Porous titanium is a kind of promising material for bone substitution, while its bio-inert property results in demand of modifications to improve the osteointegration capacity. In this study, gelatin (Gel) and nano-hydroxyapatite (nHA) were used to construct 3D micro-scaffolds in the pores of porous titanium in the ratios of Gel:nHA = 1:0, Gel:nHA = 1:1, and Gel:nHA = 1:3, respectively. Cell at...
متن کامل